A to Z of Arthritis: G is for Grapefruit Juice

15 September 2010 (updated: 12 January 2011)
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Grapefruit juice is the bad boy of breakfast beverages if you are taking certain medications. Research has revealed some 50 medications that interact with grapefruit juice including the disease-modifying drug, cyclosporine.

For some medications - including cyclosporine, the cholesterol lowering drug lovastatin (Mevacor), and the anti-anxiety medication diazepam (Valium) - grapefruit juice slows their elimination from the body, causing them to rise to dangerous levels. In others - including the allergy drug fexofadine (Telfast) or the beta blockers celiprodol (Cardem) and talinolol - grapefruit juice blocks the effects.

The more grapefruit juice you drink, the more likely you are to experience these problems. But even a single glass of grapefruit juice has the potential to affect your medications for up to three days. Your best bet: take your medications with a glass of water.