Systemic lupus erythematosus (SLE or lupus) is a disease in which the body’s natural defences (the immune system) are upset. Cells and antibodies, which are in the blood to defend the body against infection, begin to attack it instead and cause inflammation. Lupus is a systemic disease – that is, it can affect many different parts of your body.

Lupus may begin with an obvious, bad attack. It can also begin very mildly. Because it has symptoms like many other illnesses, it can be frustratingly difficult to diagnose. Often, other diseases with somewhat similar early symptoms have to be eliminated.

You can find out more about the condition in the Understanding Arthritis information booklet.